OLFM4
Summary: This gene was originally cloned from human myeloblasts and found to be selectively expressed in inflammed colonic epithelium. This gene encodes a member of the olfactomedin family. The encoded protein is an antiapoptotic factor that promotes tumor growth and is an extracellular matrix glycoprotein that facilitates cell adhesion. [provided by RefSeq, Mar 2011].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
Nameolfactomedin 4 OMIM IDMIM:614061 Ensembl IDEnsembl:ENSG00000102837 HGNC IDHGNC:HGNC:17190 PHARMGKB IDPA134984745 Map Location13q14.3 |
Gene Categories:
DRUGGABLE GENOMEGO terms in OLFM4
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Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
MF | IEA | GO:0003824 | catalytic activity |
MF | IPI | GO:0005515 | protein binding |
MF | IMP | GO:0042803 | protein homodimerization activity |
MF | IMP | GO:0045296 | cadherin binding |
CC | TAS | GO:0005576 | extracellular region |
CC | HDA | GO:0005615 | extracellular space |
Gene expression in normal tissue: OLFM4
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in OLFM4
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Database | Pathway ID | Pathway Des. |
---|---|---|
reactome | R-HSA-168249 | Innate Immune System |
reactome | R-HSA-168256 | Immune System |
reactome | R-HSA-6798695 | Neutrophil degranulation |
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Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in OLFM4
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
---|---|---|---|---|---|---|---|---|
No matching records found |