EIF5A2


Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location

GO terms in EIF5A2


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IEA GO:0003746 translation elongation factor activity
MF IPI GO:0005515 protein binding
MF IEA GO:0043022 ribosome binding
BP IEA GO:0006452 translational frameshifting
BP NAS GO:0007283 spermatogenesis
BP IGI GO:0008284 positive regulation of cell proliferation
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Gene expression in normal tissue: EIF5A2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in EIF5A2


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Database
Pathway ID
Pathway Des.
reactome R-HSA-163841 Gamma carboxylation, hypusine formation and arylsulfatase activation
reactome R-HSA-204626 Hypusine synthesis from eIF5A-lysine
reactome R-HSA-392499 Metabolism of proteins
reactome R-HSA-597592 Post-translational protein modification
wikipathways WP4239 EMT transition in Colorectal Cancer
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD634 SCHEMBL2608041 3
iGMDRD446 LY 2183240 3
iGMDRD506 Fedratinib 3
iGMDRD387 CHIR-99021 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in EIF5A2

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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