TUFT1

Summary: Tuftelin is an acidic protein that is thought to play a role in dental enamel mineralization and is implicated in caries susceptibility. It is also thought to be involved with adaptation to hypoxia, mesenchymal stem cell function, and neurotrophin nerve growth factor mediated neuronal differentiation. [provided by RefSeq, Aug 2014].

Loading, please wait...
Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Nametuftelin 1
OMIM IDMIM:600087
Ensembl IDEnsembl:ENSG00000143367
HGNC IDHGNC:HGNC:12422
PHARMGKB IDPA37084
Map Location1q21.3

Gene Categories:

DRUGGABLE GENOME

GO terms in TUFT1


Loading, please wait...
Term Type
Evidence Type
GO Term ID
GO Des.
MF IPI GO:0005515 protein binding
MF NAS GO:0030345 structural constituent of tooth enamel
BP NAS GO:0030282 bone mineralization
BP IBA GO:0035556 intracellular signal transduction
BP NAS GO:0042476 odontogenesis
CC NAS GO:0005576 extracellular region
Showing 1 to 6 of 9 rows

Gene expression in normal tissue: TUFT1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in TUFT1


Loading, please wait...
Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


Loading, please wait...
Drug ID
Drug Name
Model Num.
iGMDRD144 NSC95397 2
iGMDRD60 Quinoclamine 3
iGMDRD297 Austocystin D 3
iGMDRD398 Sepantronium 3
Showing 1 to 4 of 6 rows

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TUFT1

Loading, please wait...
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

​​​​

SITE
DATATYPES
CLASSFICATION
Map

Copyright © 2018 Modellab | All Rights Reserved

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.