TCF21

Summary: TCF21 encodes a transcription factor of the basic helix-loop-helix family. The TCF21 product is mesoderm specific, and expressed in embryonic epicardium, mesenchyme-derived tissues of lung, gut, gonad, and both mesenchymal and glomerular epithelial cells in the kidney. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Nametranscription factor 21
OMIM IDMIM:603306
Ensembl IDEnsembl:ENSG00000118526
HGNC IDHGNC:HGNC:11632
PHARMGKB IDPA36387
Map Location6q23.2

GO terms in TCF21


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Term Type
Evidence Type
GO Term ID
GO Des.
MF ISA GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding
MF ISM GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding
MF NAS GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding
MF ISS GO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
MF IDA GO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
MF IEA GO:0042826 histone deacetylase binding
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Gene expression in normal tissue: TCF21

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

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Pathways in TCF21


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD889 Compound 7d-cis 3
iGMDRD126 Tipifarnib 3
iGMDRD474 Avrainvillamide 5
iGMDRD781 Sirolimus 6
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TCF21

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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