TNFRSF12A

Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
NameTNF receptor superfamily member 12A
OMIM IDMIM:605914
Ensembl IDEnsembl:ENSG00000006327
HGNC IDHGNC:HGNC:18152
PHARMGKB IDPA134976874
Map Location16p13.3

GO terms in TNFRSF12A


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IPI GO:0005515 protein binding
BP IEA GO:0001525 angiogenesis
BP IEA GO:0006931 substrate-dependent cell migration, cell attachment to substrate
BP TAS GO:0033209 tumor necrosis factor-mediated signaling pathway
BP IDA GO:0043065 positive regulation of apoptotic process
BP IEA GO:0045765 regulation of angiogenesis
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Gene expression in normal tissue: TNFRSF12A

Gene-model tissue-cancer distribution: Bubble Plot

LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 27undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 23

Gene-drug pathway distribution

undefined12ERK MAPK signaling1Proteasome1DNA replication1

Pathways in TNFRSF12A


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Database
Pathway ID
Pathway Des.
reactome R-HSA-1280215 Cytokine Signaling in Immune system
reactome R-HSA-168256 Immune System
reactome R-HSA-5668541 TNFR2 non-canonical NF-kB pathway
reactome R-HSA-5676594 TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
wikipathways WP2036 TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway
kegg hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD103 SN-38 6
iGMDRD138 PX 12 3
iGMDRD251 ML162 3
iGMDRD255 SB225002 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TNFRSF12A

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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