OMG
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| oligodendrocyte myelin glycoprotein | MIM:164345 | Ensembl:ENSG00000126861 | HGNC:HGNC:8135 | PA31922 | 17q11.2 |
Gene Categories:
DRUGGABLE GENOMEGO terms in OMG
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IEA | GO:0007155 | cell adhesion |
| BP | TAS | GO:0050771 | negative regulation of axonogenesis |
| CC | TAS | GO:0005886 | plasma membrane |
| CC | IEA | GO:0031225 | anchored component of membrane |
Gene expression in normal tissue: OMG
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in OMG
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP2431 | Spinal Cord Injury |
| pid | p75ntrpathway | p75(NTR)-mediated signaling |
| reactome | R-HSA-162582 | Signal Transduction |
| reactome | R-HSA-193634 | Axonal growth inhibition (RHOA activation) |
| reactome | R-HSA-193697 | p75NTR regulates axonogenesis |
| reactome | R-HSA-193704 | p75 NTR receptor-mediated signalling |
| reactome | R-HSA-73887 | Death Receptor Signalling |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD286 | Nsc 632839 | 5 |
| iGMDRD414 | MST-312 | 5 |
| iGMDRD188 | Piperlongumine | 5 |
| iGMDRD100 | Zebularine | 5 |
| iGMDRD505 | Pevonedistat | 2 |
| iGMDRD886 | Compound 1541A | 2 |
| iGMDRD60 | Quinoclamine | 2 |
| iGMDRD263 | AACOCF3 | 1 |
| iGMDRD322 | FK 866 | 2 |
| iGMDRD103 | SN-38 | 4 |
| iGMDRD121 | GMX1778 | 2 |
| iGMDRD138 | PX 12 | 3 |
| iGMDRD251 | ML162 | 2 |
| iGMDRD802 | 4-methylfasudil | 1 |
| iGMDRD255 | SB225002 | 3 |
| iGMDRD446 | LY 2183240 | 3 |
| iGMDRD142 | NSC74859 | 1 |
| iGMDRD152 | 179324-69-7 | 2 |
| iGMDRD61 | Kinetin riboside | 3 |
| iGMDRD297 | Austocystin D | 5 |
| iGMDRD116 | CD437 | 3 |
| iGMDRD144 | NSC95397 | 5 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in OMG
CLASSFICATION
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Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.