COQ8B


Summary: This gene encodes a protein with two copies of a domain found in protein kinases. The encoded protein has a complete protein kinase catalytic domain, and a truncated domain that contains only the active and binding sites of the protein kinase domain, however, it is not known whether the protein has any kinase activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
OMIM IDMIM:615567
PHARMGKB IDPA134988974
Map Location19q13.2

Gene Categories:

DRUGGABLE GENOME

GO terms in COQ8B


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IDA GO:0004672 protein kinase activity
MF IEA GO:0005524 ATP binding
MF IBA GO:0016301 kinase activity
CC IBA GO:0005739 mitochondrion
CC IDA GO:0005739 mitochondrion
CC IEA GO:0005829 cytosol
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Gene expression in normal tissue: COQ8B

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined18ERK MAPK signaling1Mitosis1DNA replication1Longevity regulating pathway1WNT signaling1Purine metabolism1Proteasome1

Pathways in COQ8B


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD420 Leucascandrolide A 1
iGMDRD387 CHIR-99021 2
iGMDRD144 NSC95397 5
iGMDRD116 CD437 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in COQ8B

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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