PIM2


Summary: This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival.[provided by RefSeq, Nov 2009].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location

GO terms in PIM2


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IBA GO:0004674 protein serine/threonine kinase activity
MF IDA GO:0004674 protein serine/threonine kinase activity
MF IPI GO:0005515 protein binding
MF IEA GO:0005524 ATP binding
CC IBA GO:0005737 cytoplasm
BP IDA GO:0000082 G1/S transition of mitotic cell cycle
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Gene expression in normal tissue: PIM2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined6PI3K/MTOR signaling1Apoptosis regulation1

Pathways in PIM2


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Database
Pathway ID
Pathway Des.
wikipathways WP3640 Imatinib and Chronic Myeloid Leukemia
kegg hsa05200 Pathways in cancer - Homo sapiens (human)
kegg hsa05221 Acute myeloid leukemia - Homo sapiens (human)
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD524 ISX-9 1
iGMDRD188 Piperlongumine 2
iGMDRD341 Triacsin c 1
iGMDRD562 Navitoclax 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in PIM2

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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