MAPK8IP2
Summary: This gene encodes a scaffold protein that is thought to be involved in the regulation of the c-Jun amino-terminal kinase signaling pathway. This protein has been shown to interact with and regulate the activity of MAPK8/JNK1 and MAP2K7/MKK7 kinases. [provided by RefSeq, Jun 2017].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:607755 Ensembl IDEnsembl:ENSG00000008735 HGNC IDHGNC:HGNC:6883 PHARMGKB IDPA30627 Map Location22q13.33 | |||||
GO terms in MAPK8IP2
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | ISS | GO:0001662 | behavioral fear response |
| BP | TAS | GO:0007172 | signal complex assembly |
| BP | IEA | GO:0007254 | JNK cascade |
| BP | IEA | GO:0007617 | mating behavior |
| BP | ISS | GO:0010469 | regulation of signaling receptor activity |
| BP | IEA | GO:0032874 | positive regulation of stress-activated MAPK cascade |
Gene expression in normal tissue: MAPK8IP2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in MAPK8IP2
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in MAPK8IP2
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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