PPP3R1
Summary:
Loading, please wait...
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:601302 Ensembl IDEnsembl:ENSG00000221823 HGNC IDHGNC:HGNC:9317 PHARMGKB IDPA33681 Map Location2p14 | |||||
Gene Categories:
PROTEIN PHOSPHATASEGO terms in PPP3R1
Loading, please wait...
Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | NAS | GO:0004723 | calcium-dependent protein serine/threonine phosphatase activity |
| MF | NAS | GO:0005509 | calcium ion binding |
| MF | IPI | GO:0005515 | protein binding |
| MF | NAS | GO:0005516 | calmodulin binding |
| MF | IDA | GO:0016018 | cyclosporin A binding |
| MF | IPI | GO:0019902 | phosphatase binding |
Gene expression in normal tissue: PPP3R1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in PPP3R1
Loading, please wait...
Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-109581 | Apoptosis |
| reactome | R-HSA-109606 | Intrinsic Pathway for Apoptosis |
| reactome | R-HSA-111447 | Activation of BAD and translocation to mitochondria |
| reactome | R-HSA-111885 | Opioid Signalling |
| reactome | R-HSA-114452 | Activation of BH3-only proteins |
| reactome | R-HSA-1168372 | Downstream signaling events of B Cell Receptor (BCR) |
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in PPP3R1
Loading, please wait...
Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
Copyright © 2018 Modellab | All Rights Reserved
Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.