RABEP1
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| rabaptin, RAB GTPase binding effector protein 1 | MIM:603616 | Ensembl:ENSG00000029725 | HGNC:HGNC:17677 | PA134884097 | 17p13.2 |
Gene Categories:
GROWTH FACTORGO terms in RABEP1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IEA | GO:0006897 | endocytosis |
| BP | IEA | GO:0006915 | apoptotic process |
| BP | IEA | GO:0010469 | regulation of signaling receptor activity |
| BP | IEA | GO:0015031 | protein transport |
| BP | IMP | GO:0016192 | vesicle-mediated transport |
| BP | IEA | GO:0043547 | positive regulation of GTPase activity |
| BP | TAS | GO:0061025 | membrane fusion |
| CC | IDA | GO:0005768 | endosome |
| CC | TAS | GO:0005769 | early endosome |
| CC | IDA | GO:0030139 | endocytic vesicle |
| CC | TAS | GO:0031901 | early endosome membrane |
| CC | IMP | GO:0032991 | protein-containing complex |
| CC | IDA | GO:0043231 | intracellular membrane-bounded organelle |
| CC | IEA | GO:0055037 | recycling endosome |
| MF | IEA | GO:0005096 | GTPase activator activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0008083 | growth factor activity |
| MF | IPI | GO:0019904 | protein domain specific binding |
| MF | IPI | GO:0042803 | protein homodimerization activity |
Gene expression in normal tissue: RABEP1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in RABEP1
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-199991 | Membrane Trafficking |
| reactome | R-HSA-5653656 | Vesicle-mediated transport |
| reactome | R-HSA-8854214 | TBC/RABGAPs |
| reactome | R-HSA-9007101 | Rab regulation of trafficking |
| kegg | hsa04144 | Endocytosis - Homo sapiens (human) |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD506 | Fedratinib | 1 |
| iGMDRD280 | CYTOCHALASIN B | 5 |
| iGMDRD434 | BMS-536924 | 2 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in RABEP1
CLASSFICATION
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