CMC4
Summary: This gene was identified by involvement in some t(X;14) translocations associated with mature T-cell proliferations. This region has a complex gene structure, with a common promoter and 5' exon spliced to two different sets of 3' exons that encode two different proteins. This gene represents the downstream 8 kDa protein that localizes to mitochondria.[provided by RefSeq, Mar 2009].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| C-X9-C motif containing 4 | Ensembl:ENSG00000182712 | HGNC:HGNC:35428 | PA164723191 | Xq28 |
GO terms in CMC4
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | TAS | GO:0008283 | cell proliferation |
| CC | IDA | GO:0005739 | mitochondrion |
| CC | IBA | GO:0005758 | mitochondrial intermembrane space |
Gene expression in normal tissue: CMC4
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CMC4
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1268020 | Mitochondrial protein import |
| reactome | R-HSA-392499 | Metabolism of proteins |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD307 | Manumycin A | 6 |
| iGMDRD888 | Compound 44 | 12 |
| iGMDRD297 | Austocystin D | 6 |
| iGMDRD64 | Parbendazole | 6 |
| iGMDRD280 | CYTOCHALASIN B | 10 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CMC4
CLASSFICATION
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