CCNA2


Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members function as regulators of the cell cycle. This protein binds and activates cyclin-dependent kinase 2 and thus promotes transition through G1/S and G2/M. [provided by RefSeq, Aug 2016].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
OMIM IDMIM:123835
PHARMGKB IDPA94
Map Location4q27

GO terms in CCNA2


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Term Type
Evidence Type
GO Term ID
GO Des.
CC IBA GO:0000307 cyclin-dependent protein kinase holoenzyme complex
CC IDA GO:0000307 cyclin-dependent protein kinase holoenzyme complex
CC IEA GO:0001939 female pronucleus
CC IEA GO:0001940 male pronucleus
CC IBA GO:0005634 nucleus
CC IDA GO:0005634 nucleus
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Gene expression in normal tissue: CCNA2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in CCNA2


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Database
Pathway ID
Pathway Des.
pid atf2_pathway ATF-2 transcription factor network
pid atr_pathway ATR signaling pathway
pid e2f_pathway E2F transcription factor network
pid foxm1pathway FOXM1 transcription factor network
pid fra_pathway Validated transcriptional targets of AP1 family members Fra1 and Fra2
pid il2_stat5pathway IL2 signaling events mediated by STAT5
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD405 PIK-75 3
iGMDRD394 BX-795 2
iGMDRD546 BMS-754807 3
iGMDRD577 BIX01294 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in CCNA2

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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