ULK1

Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Nameunc-51 like autophagy activating kinase 1
OMIM IDMIM:603168
Ensembl IDEnsembl:ENSG00000177169
HGNC IDHGNC:HGNC:12558
PHARMGKB IDPA37198
Map Location12q24.33

GO terms in ULK1


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Term Type
Evidence Type
GO Term ID
GO Des.
BP IBA GO:0000045 autophagosome assembly
BP NAS GO:0006468 protein phosphorylation
BP IDA GO:0006914 autophagy
BP IMP GO:0006914 autophagy
BP ISS GO:0006914 autophagy
BP IEA GO:0007165 signal transduction
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Gene expression in normal tissue: ULK1

16 tissues mixtureadiposeadrenalbrainbreastcolonheartkidneyliverlunglymph nodeovaryprostateskeletal muscletestesthyroidwhite blood cells

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 15LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 12UTERUtissue: UTERU cancer: UTERUS model num: 0UTERUStissue: UTERUS cancer: Endometrial Carcinoma (UCEC) model num: 2

Gene-drug pathway distribution

undefined8Other, kinases1Apoptosis regulation1Mitosis1

Pathways in ULK1


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Database
Pathway ID
Pathway Des.
kegg hsa04137 Mitophagy - animal - Homo sapiens (human)
kegg hsa04140 Autophagy - animal - Homo sapiens (human)
kegg hsa04150 mTOR signaling pathway - Homo sapiens (human)
kegg hsa04152 AMPK signaling pathway - Homo sapiens (human)
kegg hsa04211 Longevity regulating pathway - Homo sapiens (human)
pid mtor_4pathway mTOR signaling pathway
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD300 Tozasertib 3
iGMDRD562 Navitoclax 2
iGMDRD61 Kinetin riboside 5
iGMDRD577 BIX01294 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ULK1

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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