GO terms in ULK1


Term TypeEvidence TypeGO Term IDGO Des.
BPIBAGO:0000045autophagosome assembly
BPNASGO:0006468protein phosphorylation
BPIDAGO:0006914autophagy
BPIMPGO:0006914autophagy
BPISSGO:0006914autophagy
BPIEAGO:0007165signal transduction
BPIMPGO:0008104protein localization
BPIBAGO:0010506regulation of autophagy
BPIMPGO:0016236macroautophagy
BPTASGO:0016236macroautophagy
BPTASGO:0016241regulation of macroautophagy
BPIDAGO:0018105peptidyl-serine phosphorylation
BPIDAGO:0018107peptidyl-threonine phosphorylation
BPIEAGO:0031102neuron projection regeneration
BPIMPGO:0031175neuron projection development
BPIDAGO:0031333negative regulation of protein complex assembly
BPISSGO:0031669cellular response to nutrient levels
BPISSGO:0042594response to starvation
BPIBAGO:0046777protein autophosphorylation
BPIDAGO:0046777protein autophosphorylation
BPIBAGO:0048675axon extension
BPIGIGO:0075044autophagy of host cells involved in interaction with symbiont
BPIEAGO:2000786positive regulation of autophagosome assembly
CCIBAGO:0000407phagophore assembly site
CCNASGO:0005737cytoplasm
CCTASGO:0005741mitochondrial outer membrane
CCIDAGO:0005776autophagosome
CCTASGO:0005789endoplasmic reticulum membrane
CCIBAGO:0005829cytosol
CCIDAGO:0005829cytosol
CCTASGO:0005829cytosol
CCIBAGO:0016020membrane
CCIEAGO:0030424axon
CCIDAGO:0032045guanyl-nucleotide exchange factor complex
CCIDAGO:0034045phagophore assembly site membrane
CCTASGO:0055037recycling endosome
CCIDAGO:0097629extrinsic component of omegasome membrane
CCIDAGO:0097632extrinsic component of phagophore assembly site membrane
CCIDAGO:0097635extrinsic component of autophagosome membrane
CCIPIGO:1990316Atg1/ULK1 kinase complex
MFIBAGO:0004674protein serine/threonine kinase activity
MFIDAGO:0004674protein serine/threonine kinase activity
MFNASGO:0004674protein serine/threonine kinase activity
MFTASGO:0004674protein serine/threonine kinase activity
MFIPIGO:0005515protein binding
MFIEAGO:0005524ATP binding
MFTASGO:0016301kinase activity
MFIPIGO:0017137Rab GTPase binding
MFIPIGO:0042802identical protein binding
MFIPIGO:0044877protein-containing complex binding
MFIPIGO:0051020GTPase binding

Gene expression in normal tissue: ULK1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in ULK1


DatabasePathway IDPathway Des.
kegghsa04137Mitophagy - animal - Homo sapiens (human)
kegghsa04140Autophagy - animal - Homo sapiens (human)
kegghsa04150mTOR signaling pathway - Homo sapiens (human)
kegghsa04152AMPK signaling pathway - Homo sapiens (human)
kegghsa04211Longevity regulating pathway - Homo sapiens (human)
pidmtor_4pathwaymTOR signaling pathway
wikipathwaysWP1471Target Of Rapamycin (TOR) Signaling
wikipathwaysWP2509Nanoparticle triggered autophagic cell death
wikipathwaysWP3844PI3K-AKT-mTOR signaling pathway and therapeutic opportunities
wikipathwaysWP3932Focal Adhesion-PI3K-Akt-mTOR-signaling pathway
wikipathwaysWP615Senescence and Autophagy in Cancer
reactomeR-HSA-1632852Macroautophagy
reactomeR-HSA-199991Membrane Trafficking
reactomeR-HSA-5205647Mitophagy
reactomeR-HSA-5653656Vesicle-mediated transport
reactomeR-HSA-8854214TBC/RABGAPs
reactomeR-HSA-8876198RAB GEFs exchange GTP for GDP on RABs
reactomeR-HSA-8934903Receptor Mediated Mitophagy
reactomeR-HSA-8953897Cellular responses to external stimuli
reactomeR-HSA-9007101Rab regulation of trafficking

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD300Tozasertib3
iGMDRD562Navitoclax2
iGMDRD61Kinetin riboside5
iGMDRD577BIX012942
iGMDRD506Fedratinib2
iGMDRD414MST-3123
iGMDRD286Nsc 6328393
iGMDRD77Itraconazole3
iGMDRD434BMS-5369242
iGMDRD150RITA3
iGMDRD210AC556491

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ULK1

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