ERRFI1

Summary: ERRFI1 is a cytoplasmic protein whose expression is upregulated with cell growth (Wick et al., 1995 [PubMed 7641805]). It shares significant homology with the protein product of rat gene-33, which is induced during cell stress and mediates cell signaling (Makkinje et al., 2000 [PubMed 10749885]; Fiorentino et al., 2000 [PubMed 11003669]).[supplied by OMIM, Mar 2008].

Loading, please wait...
Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
NameERBB receptor feedback inhibitor 1
OMIM IDMIM:608069
Ensembl IDEnsembl:ENSG00000116285
HGNC IDHGNC:HGNC:18185
PHARMGKB IDPA142671904
Map Location1p36.23

Gene Categories:

KINASETYROSINE KINASE

GO terms in ERRFI1


Loading, please wait...
Term Type
Evidence Type
GO Term ID
GO Des.
CC IEA GO:0005634 nucleus
CC ISS GO:0005737 cytoplasm
CC IDA GO:0005829 cytosol
CC IBA GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
CC ISS GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
BP IDA GO:0007175 negative regulation of epidermal growth factor-activated receptor activity
Showing 1 to 6 of 32 rows rows per page

Gene expression in normal tissue: ERRFI1

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 22LIVEtissue: LIVE cancer: LIVER model num: 0LIVERtissue: LIVER cancer: undefined model num: 3BILIARY_TRACtissue: BILIARY_TRAC cancer: BILIARY_TRACT model num: 0BILIARY_TRACTtissue: BILIARY_TRACT cancer: Cholangiocarcinoma (CHOL) model num: 1

Gene-drug pathway distribution

undefined5ERK MAPK signaling4IGFR signaling3Mitosis2JNK and p38 signaling2DNA replication2Protein stability and degradation2Apoptosis regulation1PPAR signaling pathway1EGFR signaling1

Pathways in ERRFI1


Loading, please wait...
Database
Pathway ID
Pathway Des.
wikipathways WP2261 Signaling Pathways in Glioblastoma
wikipathways WP437 EGF-EGFR Signaling Pathway
netpath Pathway_EGFR1 EGFR1
Showing 1 to 3 of 3 rows

Gene-Drug: Aster Plot


Loading, please wait...
Drug ID
Drug Name
Model Num.
iGMDRD519 GDC-0941 1
iGMDRD608 Refametinib 1
iGMDRD317 CCT 018159 1
iGMDRD352 PD-0325901 1
Showing 1 to 4 of 26 rows rows per page

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ERRFI1

Loading, please wait...
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

​​​​

SITE
DATATYPES
CLASSFICATION
Map

Copyright © 2018 Modellab | All Rights Reserved

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.