iGMDRD352
| Standard Name | CHEMBL | Pubchem CID | DRUGBANK ID | Drug Status | Drug Type |
|---|---|---|---|---|---|
| PD-0325901 | CHEMBL507361 | 9826530 | DB07101 | Alone | Small Molecule |
Drug Class:
Kinase inhibitorDrug Pathways:
ERK MAPK signalingDrug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
| Gene ID | Gene Name | Model Num. |
|---|---|---|
| 55510 | DDX43 | 1 |
| 2956 | MSH6 | 1 |
| 103 | ADAR | 1 |
| 3845 | KRAS | 1 |
| 5295 | PIK3R1 | 1 |
| 8266 | UBL4A | 1 |
| 6597 | SMARCA4 | 1 |
| 4771 | NF2 | 1 |
| 6598 | SMARCB1 | 1 |
| 8242 | KDM5C | 1 |
| 4851 | NOTCH1 | 1 |
| 5605 | MAP2K2 | 1 |
| 55294 | FBXW7 | 1 |
| 1021 | CDK6 | 1 |
| 4610 | MYCL | 1 |
| 25937 | WWTR1 | 1 |
| 4300 | MLLT3 | 1 |
| 51343 | FZR1 | 1 |
| 2210 | FCGR1B | 1 |
| 7428 | VHL | 1 |
| 2064 | ERBB2 | 1 |
| 6416 | MAP2K4 | 1 |
| 2778 | GNAS | 1 |
| 1029 | CDKN2A | 1 |
| 861 | RUNX1 | 1 |
| 10018 | BCL2L11 | 1 |
| 5834 | PYGB | 2 |
| 7157 | TP53 | 1 |
| 3673 | ITGA2 | 1 |
| 6794 | STK11 | 1 |
| 3791 | KDR | 1 |
| 8061 | FOSL1 | 1 |
| 4292 | MLH1 | 1 |
| 1019 | CDK4 | 1 |
| 5604 | MAP2K1 | 2 |
| 162979 | ZNF296 | 1 |
| 4904 | YBX1 | 1 |
| 4089 | SMAD4 | 2 |
| 3417 | IDH1 | 1 |
| 8731 | RNMT | 1 |
| 5290 | PIK3CA | 1 |
| 1956 | EGFR | 2 |
| 4609 | MYC | 1 |
| 54206 | ERRFI1 | 1 |
| 1031 | CDKN2C | 1 |
| 5156 | PDGFRA | 1 |
| 673 | BRAF | 3 |
| 5728 | PTEN | 2 |
| 208 | AKT2 | 1 |
| 1869 | E2F1 | 1 |
| 596 | BCL2 | 1 |
| 1027 | CDKN1B | 1 |
| 2067 | ERCC1 | 1 |
| 9223 | MAGI1 | 1 |
| 3717 | JAK2 | 1 |
| 100862685 | ERVK-19 | 1 |
| 5054 | SERPINE1 | 1 |
| 5925 | RB1 | 1 |
| 4893 | NRAS | 1 |
| 2065 | ERBB3 | 1 |
| 7403 | KDM6A | 1 |
| 142 | PARP1 | 2 |
| 374 | AREG | 1 |
| 595 | CCND1 | 1 |
| 4763 | NF1 | 2 |
| 4613 | MYCN | 1 |
| 3265 | HRAS | 2 |
| 4193 | MDM2 | 1 |
| 1499 | CTNNB1 | 1 |
| 5624 | PROC | 1 |
Gene in drug-gene network: Network Plot
Models in PD-0325901
CLASSFICATION
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