iGMDRD608


Canonical SMILES: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F

InChI: InChI=1S/C19H20F3IN2O5S/c1-30-15-7-13(21)16(22)18(24-14-3-2-10(23)6-12(14)20)17(15)25-31(28,29)19(4-5-19)8-11(27)9-26/h2-3,6-7,11,24-27H,4-5,8-9H2,1H3/t11-/m0/s1

InChI Key: RDSACQWTXKSHJT-NSHDSACASA-N

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Standard Name
Pubchem CID
Drug Status
Drug Type
Standard NameRefametinib
Pubchem CID44182300
Drug StatusAlone
Drug TypeSmall Molecule


Drug Pathways:

ERK MAPK signaling

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
567 B2M 1
103 ADAR 1
3845 KRAS 8
4851 NOTCH1 1
Showing 1 to 4 of 52 rows rows per page

Gene in drug-gene network: Network Plot

Models in Refametinib

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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