iGMDRD324


Canonical SMILES: C1CC1CONC(=O)C2=C(C(=C(C=C2)F)F)NC3=C(C=C(C=C3)I)Cl

InChI: InChI=1S/C17H14ClF2IN2O2/c18-12-7-10(21)3-6-14(12)22-16-11(4-5-13(19)15(16)20)17(24)23-25-8-9-1-2-9/h3-7,9,22H,1-2,8H2,(H,23,24)

InChI Key: GFMMXOIFOQCCGU-UHFFFAOYSA-N

Standard NameCHEMBLPubchem CIDDRUGBANK IDDrug StatusDrug Type
CI-1040CHEMBL105442 6918450DB12429AloneSmall Molecule



Drug Pathways:

ERK MAPK signaling

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
103ADAR1
3845KRAS2
4771NF21
9757KMT2B1
2625GATA31
55294FBXW71
2033EP3001
4610MYCL1
25937WWTR11
7416VDAC11
2064ERBB21
472ATM1
10413YAP11
1029CDKN2A2
5834PYGB1
4088SMAD31
3673ITGA21
54498SMOX1
4904YBX11
4089SMAD43
6654SOS11
5290PIK3CA1
1956EGFR1
3553IL1B1
673BRAF5
5728PTEN2
1869E2F11
1027CDKN1B1
2067ERCC12
100862685ERVK-191
5054SERPINE11
4893NRAS3
2065ERBB31
142PARP11
374AREG1
2146EZH21

Gene in drug-gene network: Network Plot

Models in CI-1040

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