iGMDRD136
| Standard Name | CHEMBL | Pubchem CID | Drug Status | Drug Type |
|---|---|---|---|---|
| Nutlin-3 | CHEMBL191334 | 216345 | Alone | Small Molecule |
Drug Targets:
MDM2Drug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
| Gene ID | Gene Name | Model Num. |
|---|---|---|
| 2956 | MSH6 | 1 |
| 3845 | KRAS | 1 |
| 5295 | PIK3R1 | 1 |
| 6597 | SMARCA4 | 1 |
| 4771 | NF2 | 1 |
| 6598 | SMARCB1 | 1 |
| 8242 | KDM5C | 1 |
| 4851 | NOTCH1 | 1 |
| 55294 | FBXW7 | 1 |
| 1021 | CDK6 | 1 |
| 4610 | MYCL | 1 |
| 4300 | MLLT3 | 1 |
| 51343 | FZR1 | 1 |
| 7428 | VHL | 1 |
| 2064 | ERBB2 | 1 |
| 6416 | MAP2K4 | 1 |
| 2778 | GNAS | 1 |
| 1029 | CDKN2A | 1 |
| 861 | RUNX1 | 1 |
| 7157 | TP53 | 1 |
| 6794 | STK11 | 1 |
| 4292 | MLH1 | 1 |
| 1019 | CDK4 | 1 |
| 4089 | SMAD4 | 1 |
| 3417 | IDH1 | 1 |
| 8731 | RNMT | 1 |
| 5290 | PIK3CA | 1 |
| 1956 | EGFR | 1 |
| 4609 | MYC | 1 |
| 1031 | CDKN2C | 1 |
| 5156 | PDGFRA | 1 |
| 673 | BRAF | 1 |
| 5728 | PTEN | 1 |
| 208 | AKT2 | 1 |
| 3717 | JAK2 | 1 |
| 5925 | RB1 | 1 |
| 4893 | NRAS | 1 |
| 7403 | KDM6A | 1 |
| 595 | CCND1 | 1 |
| 4763 | NF1 | 1 |
| 4613 | MYCN | 1 |
| 3265 | HRAS | 1 |
| 4193 | MDM2 | 1 |
| 1499 | CTNNB1 | 1 |
| 5624 | PROC | 1 |
Gene in drug-gene network: Network Plot
Models in Nutlin-3
CLASSFICATION
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