ANKRD27
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| ankyrin repeat domain 27 | Ensembl:ENSG00000105186 | HGNC:HGNC:25310 | PA134893411 | 19q13.11 |
GO terms in ANKRD27
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IDA | GO:0005764 | lysosome |
| CC | IBA | GO:0005769 | early endosome |
| CC | IDA | GO:0005769 | early endosome |
| CC | IBA | GO:0005770 | late endosome |
| CC | IDA | GO:0005770 | late endosome |
| CC | TAS | GO:0005829 | cytosol |
| CC | IBA | GO:0005886 | plasma membrane |
| CC | IDA | GO:0005886 | plasma membrane |
| CC | HDA | GO:0016020 | membrane |
| CC | IBA | GO:0030133 | transport vesicle |
| CC | IEA | GO:0030659 | cytoplasmic vesicle membrane |
| CC | IEA | GO:0042470 | melanosome |
| CC | IBA | GO:0043005 | neuron projection |
| CC | IEA | GO:0043005 | neuron projection |
| CC | IBA | GO:0097422 | tubular endosome |
| CC | IDA | GO:0097422 | tubular endosome |
| BP | IEA | GO:0015031 | protein transport |
| BP | IDA | GO:0035544 | negative regulation of SNARE complex assembly |
| BP | IEA | GO:0035646 | endosome to melanosome transport |
| BP | IEA | GO:0043547 | positive regulation of GTPase activity |
| BP | IBA | GO:0045022 | early endosome to late endosome transport |
| BP | IDA | GO:0045022 | early endosome to late endosome transport |
| BP | IBA | GO:0048812 | neuron projection morphogenesis |
| BP | IEA | GO:0048812 | neuron projection morphogenesis |
| BP | IEA | GO:0050775 | positive regulation of dendrite morphogenesis |
| BP | IBA | GO:1990126 | retrograde transport, endosome to plasma membrane |
| BP | IMP | GO:1990126 | retrograde transport, endosome to plasma membrane |
| MF | IBA | GO:0000149 | SNARE binding |
| MF | IBA | GO:0005085 | guanyl-nucleotide exchange factor activity |
| MF | IDA | GO:0005085 | guanyl-nucleotide exchange factor activity |
| MF | IEA | GO:0005096 | GTPase activator activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | TAS | GO:0017112 | Rab guanyl-nucleotide exchange factor activity |
| MF | IBA | GO:0017137 | Rab GTPase binding |
| MF | IDA | GO:0017137 | Rab GTPase binding |
Gene expression in normal tissue: ANKRD27
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ANKRD27
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-199991 | Membrane Trafficking |
| reactome | R-HSA-5653656 | Vesicle-mediated transport |
| reactome | R-HSA-8876198 | RAB GEFs exchange GTP for GDP on RABs |
| reactome | R-HSA-9007101 | Rab regulation of trafficking |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ANKRD27
CLASSFICATION
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