RAB11FIP1
Summary: This gene encodes one of the Rab11-family interacting proteins (Rab11-FIPs), which play a role in the Rab-11 mediated recycling of vesicles. The encoded protein may be involved in endocytic sorting, trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR), and transport between the recycling endosome and the trans-Golgi network. Alternative splicing results in multiple transcript variants. A pseudogene is described on the X chromosome. [provided by RefSeq, Dec 2013].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| RAB11 family interacting protein 1 | MIM:608737 | Ensembl:ENSG00000156675 | HGNC:HGNC:30265 | PA134937501 | 8p11.23 |
GO terms in RAB11FIP1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IPI | GO:0005515 | protein binding |
| MF | IBA | GO:0017137 | Rab GTPase binding |
| BP | IEA | GO:0015031 | protein transport |
| BP | IBA | GO:0045055 | regulated exocytosis |
| BP | IDA | GO:0070164 | negative regulation of adiponectin secretion |
| CC | IDA | GO:0005829 | cytosol |
| CC | IEA | GO:0030670 | phagocytic vesicle membrane |
| CC | IBA | GO:0043231 | intracellular membrane-bounded organelle |
| CC | IDA | GO:0043231 | intracellular membrane-bounded organelle |
| CC | IEA | GO:0055037 | recycling endosome |
Gene expression in normal tissue: RAB11FIP1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in RAB11FIP1
CLASSFICATION
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