RAB11FIP1


Summary: This gene encodes one of the Rab11-family interacting proteins (Rab11-FIPs), which play a role in the Rab-11 mediated recycling of vesicles. The encoded protein may be involved in endocytic sorting, trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR), and transport between the recycling endosome and the trans-Golgi network. Alternative splicing results in multiple transcript variants. A pseudogene is described on the X chromosome. [provided by RefSeq, Dec 2013].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
RAB11 family interacting protein 1MIM:608737Ensembl:ENSG00000156675HGNC:HGNC:30265PA1349375018p11.23

GO terms in RAB11FIP1


Term TypeEvidence TypeGO Term IDGO Des.
MFIPIGO:0005515protein binding
MFIBAGO:0017137Rab GTPase binding
BPIEAGO:0015031protein transport
BPIBAGO:0045055regulated exocytosis
BPIDAGO:0070164negative regulation of adiponectin secretion
CCIDAGO:0005829cytosol
CCIEAGO:0030670phagocytic vesicle membrane
CCIBAGO:0043231intracellular membrane-bounded organelle
CCIDAGO:0043231intracellular membrane-bounded organelle
CCIEAGO:0055037recycling endosome

Gene expression in normal tissue: RAB11FIP1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in RAB11FIP1


DatabasePathway IDPathway Des.
kegghsa04144Endocytosis - Homo sapiens (human)

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD409Saracatinib2

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in RAB11FIP1

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