ENO2

Summary: This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. [provided by RefSeq, Jul 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Nameenolase 2
OMIM IDMIM:131360
Ensembl IDEnsembl:ENSG00000111674
HGNC IDHGNC:HGNC:3353
PHARMGKB IDPA27788
Map Location12p13.31

GO terms in ENO2


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IEA GO:0000287 magnesium ion binding
MF ISS GO:0004634 phosphopyruvate hydratase activity
MF TAS GO:0004634 phosphopyruvate hydratase activity
MF IPI GO:0005515 protein binding
CC IEA GO:0000015 phosphopyruvate hydratase complex
CC IEA GO:0001917 photoreceptor inner segment
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Gene expression in normal tissue: ENO2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in ENO2


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Database
Pathway ID
Pathway Des.
netpath Pathway_TCR TCR
kegg hsa00010 Glycolysis / Gluconeogenesis - Homo sapiens (human)
kegg hsa03018 RNA degradation - Homo sapiens (human)
kegg hsa04066 HIF-1 signaling pathway - Homo sapiens (human)
humancyc PWY66-399 gluconeogenesis
humancyc PWY66-400 glycolysis
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD536 PLX-4720 2
iGMDRD491 TAE-684 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ENO2

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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