MPC2
Summary:
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:614737 Ensembl IDEnsembl:ENSG00000143158 HGNC IDHGNC:HGNC:24515 PHARMGKB IDPA142672547 Map Location1q24.2 | |||||
Gene Categories:
TRANSPORTERGO terms in MPC2
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0050833 | pyruvate transmembrane transporter activity |
| CC | HDA | GO:0005634 | nucleus |
| CC | IDA | GO:0005739 | mitochondrion |
| CC | IBA | GO:0031305 | integral component of mitochondrial inner membrane |
| BP | IEA | GO:0006850 | mitochondrial pyruvate transmembrane transport |
| BP | IEA | GO:0035774 | positive regulation of insulin secretion involved in cellular response to glucose stimulus |
Gene expression in normal tissue: MPC2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in MPC2
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1428517 | The citric acid (TCA) cycle and respiratory electron transport |
| reactome | R-HSA-1430728 | Metabolism |
| reactome | R-HSA-70268 | Pyruvate metabolism |
| reactome | R-HSA-71406 | Pyruvate metabolism and Citric Acid (TCA) cycle |
| wikipathways | WP534 | Glycolysis and Gluconeogenesis |
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Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD536 | PLX-4720 | 2 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in MPC2
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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