TOMM7
Summary: This gene encodes a subunit of the translocase of the outer mitochondrial membrane. The encoded protein regulates the assembly and stability of the translocase complex. [provided by RefSeq, Oct 2012].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| translocase of outer mitochondrial membrane 7 | MIM:607980 | Ensembl:ENSG00000196683 | HGNC:HGNC:21648 | PA134864325 | 7p15.3 |
Gene Categories:
TRANSPORTERGO terms in TOMM7
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IPI | GO:0005515 | protein binding |
| MF | TAS | GO:0008320 | protein transmembrane transporter activity |
| CC | IDA | GO:0005739 | mitochondrion |
| CC | TAS | GO:0005741 | mitochondrial outer membrane |
| CC | IDA | GO:0005742 | mitochondrial outer membrane translocase complex |
| CC | TAS | GO:0005742 | mitochondrial outer membrane translocase complex |
| BP | TAS | GO:0006626 | protein targeting to mitochondrion |
| BP | IMP | GO:0031647 | regulation of protein stability |
| BP | IMP | GO:0098779 | positive regulation of mitophagy in response to mitochondrial depolarization |
| BP | IMP | GO:1903955 | positive regulation of protein targeting to mitochondrion |
Gene expression in normal tissue: TOMM7
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in TOMM7
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1268020 | Mitochondrial protein import |
| reactome | R-HSA-392499 | Metabolism of proteins |
| reactome | R-HSA-5205647 | Mitophagy |
| reactome | R-HSA-5205685 | Pink/Parkin Mediated Mitophagy |
| kegg | hsa04137 | Mitophagy - animal - Homo sapiens (human) |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in TOMM7
CLASSFICATION
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