TOMM7

Summary: This gene encodes a subunit of the translocase of the outer mitochondrial membrane. The encoded protein regulates the assembly and stability of the translocase complex. [provided by RefSeq, Oct 2012].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Nametranslocase of outer mitochondrial membrane 7
OMIM IDMIM:607980
Ensembl IDEnsembl:ENSG00000196683
HGNC IDHGNC:HGNC:21648
PHARMGKB IDPA134864325
Map Location7p15.3

Gene Categories:

TRANSPORTER

GO terms in TOMM7


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IPI GO:0005515 protein binding
MF TAS GO:0008320 protein transmembrane transporter activity
CC IDA GO:0005739 mitochondrion
CC TAS GO:0005741 mitochondrial outer membrane
CC IDA GO:0005742 mitochondrial outer membrane translocase complex
CC TAS GO:0005742 mitochondrial outer membrane translocase complex
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Gene expression in normal tissue: TOMM7

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

ERK MAPK signaling1

Pathways in TOMM7


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Database
Pathway ID
Pathway Des.
reactome R-HSA-1268020 Mitochondrial protein import
reactome R-HSA-392499 Metabolism of proteins
reactome R-HSA-5205647 Mitophagy
reactome R-HSA-5205685 Pink/Parkin Mediated Mitophagy
kegg hsa04137 Mitophagy - animal - Homo sapiens (human)
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD536 PLX-4720 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TOMM7

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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