HMGCS1

Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Name3-hydroxy-3-methylglutaryl-CoA synthase 1
OMIM IDMIM:142940
Ensembl IDEnsembl:ENSG00000112972
HGNC IDHGNC:HGNC:5007
PHARMGKB IDPA29337
Map Location5p12

GO terms in HMGCS1


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Term Type
Evidence Type
GO Term ID
GO Des.
CC TAS GO:0005737 cytoplasm
CC IBA GO:0005829 cytosol
CC TAS GO:0005829 cytosol
BP IEA GO:0001889 liver development
BP IBA GO:0006084 acetyl-CoA metabolic process
BP NAS GO:0006629 lipid metabolic process
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Gene expression in normal tissue: HMGCS1

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 1

Gene-drug pathway distribution

ERK MAPK signaling1

Pathways in HMGCS1


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Database
Pathway ID
Pathway Des.
humancyc PWY-5910 superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate)
humancyc PWY-922 mevalonate pathway
humancyc PWY66-367 ketogenesis
humancyc PWY66-5 superpathway of cholesterol biosynthesis
kegg hsa00072 Synthesis and degradation of ketone bodies - Homo sapiens (human)
kegg hsa00280 Valine, leucine and isoleucine degradation - Homo sapiens (human)
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD536 PLX-4720 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in HMGCS1

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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