STMN3

Summary: This gene encodes a protein which is a member of the stathmin protein family. Members of this protein family form a complex with tubulins at a ratio of 2 tubulins for each stathmin protein. Microtubules require the ordered assembly of alpha- and beta-tubulins, and formation of a complex with stathmin disrupts microtubule formation and function. A pseudogene of this gene is located on chromosome 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namestathmin 3
OMIM IDMIM:608362
Ensembl IDEnsembl:ENSG00000197457
HGNC IDHGNC:HGNC:15926
PHARMGKB IDPA38049
Map Location20q13.33

GO terms in STMN3


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Term Type
Evidence Type
GO Term ID
GO Des.
BP IBA GO:0007019 microtubule depolymerization
BP TAS GO:0007399 nervous system development
BP IEA GO:0031110 regulation of microtubule polymerization or depolymerization
BP ISS GO:0031122 cytoplasmic microtubule organization
BP IBA GO:0031175 neuron projection development
BP ISS GO:0031175 neuron projection development
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Gene expression in normal tissue: STMN3

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

ERK MAPK signaling1

Pathways in STMN3


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD536 PLX-4720 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in STMN3

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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