DHFR2
Summary:
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:616588 Ensembl IDEnsembl:ENSG00000178700 HGNC IDHGNC:HGNC:27309 PHARMGKB IDPA134889916 Map Location3q11.2 | |||||
Gene Categories:
DRUGGABLE GENOMEGO terms in DHFR2
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IEA | GO:0006730 | one-carbon metabolic process |
| BP | IDA | GO:0046105 | thymidine biosynthetic process |
| BP | IBA | GO:0046452 | dihydrofolate metabolic process |
| BP | IDA | GO:0046653 | tetrahydrofolate metabolic process |
| BP | IBA | GO:0046654 | tetrahydrofolate biosynthetic process |
| BP | IEA | GO:0046654 | tetrahydrofolate biosynthetic process |
Gene expression in normal tissue: DHFR2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in DHFR2
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1430728 | Metabolism |
| reactome | R-HSA-196757 | Metabolism of folate and pterines |
| reactome | R-HSA-196849 | Metabolism of water-soluble vitamins and cofactors |
| reactome | R-HSA-196854 | Metabolism of vitamins and cofactors |
| wikipathways | WP2525 | Trans-sulfuration and one carbon metabolism |
| wikipathways | WP3940 | One carbon metabolism and related pathways |
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD536 | PLX-4720 | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in DHFR2
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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