GO terms in FNTB


Term TypeEvidence TypeGO Term IDGO Des.
BPIEAGO:0008285negative regulation of cell proliferation
BPIEAGO:0010035response to inorganic substance
BPIEAGO:0014070response to organic cyclic compound
BPIBAGO:0018342protein prenylation
BPIBAGO:0018343protein farnesylation
BPIDAGO:0018343protein farnesylation
BPIEAGO:0034097response to cytokine
BPIEAGO:0042060wound healing
BPIEAGO:0045787positive regulation of cell cycle
BPIEAGO:0048146positive regulation of fibroblast proliferation
BPIEAGO:0051770positive regulation of nitric-oxide synthase biosynthetic process
CCTASGO:0005829cytosol
CCIDAGO:0005875microtubule associated complex
CCIBAGO:0005965protein farnesyltransferase complex
CCIDAGO:0005965protein farnesyltransferase complex
MFIEAGO:0004311farnesyltranstransferase activity
MFIBAGO:0004659prenyltransferase activity
MFIBAGO:0004660protein farnesyltransferase activity
MFIDAGO:0004660protein farnesyltransferase activity
MFIDAGO:0004660protein farnesyltransferase activity
MFIPIGO:0005515protein binding
MFIEAGO:0008144drug binding
MFIDAGO:0008270zinc ion binding
MFIEAGO:0019840isoprenoid binding
MFIEAGO:0042277peptide binding

Gene expression in normal tissue: FNTB

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in FNTB


DatabasePathway IDPathway Des.
reactomeR-HSA-162582Signal Transduction
reactomeR-HSA-2187338Visual phototransduction
reactomeR-HSA-2514856The phototransduction cascade
reactomeR-HSA-2514859Inactivation, recovery and regulation of the phototransduction cascade
reactomeR-HSA-372790Signaling by GPCR
reactomeR-HSA-388396GPCR downstream signalling
reactomeR-HSA-418594G alpha (i) signalling events
kegghsa00900Terpenoid backbone biosynthesis - Homo sapiens (human)

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD120Lonafarnib1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in FNTB

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