FRRS1L
Summary: This gene encodes a component of the outer-core of an alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor protein in the brain. The encoded protein is thought to interact with inner-core components of the receptor, and play a role in the modulation of glutamate signaling. Mutations in this gene are associated with early infantile epileptic encephalopathy 37. [provided by RefSeq, Jul 2016].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:604574 Ensembl IDEnsembl:ENSG00000260230 HGNC IDHGNC:HGNC:1362 PHARMGKB IDPA25979 Map Location9q31.3 | |||||
GO terms in FRRS1L
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IMP | GO:1900449 | regulation of glutamate receptor signaling pathway |
| CC | ND | GO:0005575 | cellular_component |
| CC | IEA | GO:0005886 | plasma membrane |
| CC | IEA | GO:0016021 | integral component of membrane |
| CC | IEA | GO:0030054 | cell junction |
| CC | IEA | GO:0045202 | synapse |
Gene expression in normal tissue: FRRS1L
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in FRRS1L
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in FRRS1L
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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