ALPG
Summary: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The product of this gene is a membrane bound glycosylated enzyme, localized to testis, thymus and certain germ cell tumors, that is closely related to both the placental and intestinal forms of alkaline phosphatase. [provided by RefSeq, Jul 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| alkaline phosphatase, germ cell | MIM:171810 | Ensembl:ENSG00000163286 | HGNC:HGNC:441 | PA24731 | 2q37.1 |
GO terms in ALPG
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IDA | GO:0004035 | alkaline phosphatase activity |
| MF | NAS | GO:0004035 | alkaline phosphatase activity |
| MF | IEA | GO:0046872 | metal ion binding |
| CC | TAS | GO:0005576 | extracellular region |
| CC | IDA | GO:0005886 | plasma membrane |
| CC | TAS | GO:0005886 | plasma membrane |
| CC | IEA | GO:0031225 | anchored component of membrane |
| BP | IEA | GO:0016311 | dephosphorylation |
Gene expression in normal tissue: ALPG
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ALPG
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP2877 | Vitamin D Receptor Pathway |
| kegg | hsa00730 | Thiamine metabolism - Homo sapiens (human) |
| kegg | hsa00790 | Folate biosynthesis - Homo sapiens (human) |
| reactome | R-HSA-163125 | Post-translational modification: synthesis of GPI-anchored proteins |
| reactome | R-HSA-392499 | Metabolism of proteins |
| reactome | R-HSA-597592 | Post-translational protein modification |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ALPG
CLASSFICATION
Copyright © 2018 Modellab | All Rights Reserved
Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.