FNDC5
Summary: This gene encodes a secreted protein that is released from muscle cells during exercise. The encoded protein may participate in the development of brown fat. Translation of the precursor protein initiates at a non-AUG start codon at a position that is conserved as an AUG start codon in other organisms. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| fibronectin type III domain containing 5 | MIM:611906 | Ensembl:ENSG00000160097 | HGNC:HGNC:20240 | PA134924607 | 1p35.1 |
GO terms in FNDC5
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | ND | GO:0003674 | molecular_function |
| MF | IEA | GO:0005179 | hormone activity |
| CC | ISS | GO:0005576 | extracellular region |
| CC | IEA | GO:0005778 | peroxisomal membrane |
| CC | IBA | GO:0005783 | endoplasmic reticulum |
| CC | ISS | GO:0005783 | endoplasmic reticulum |
| CC | IBA | GO:0005886 | plasma membrane |
| CC | ISS | GO:0005886 | plasma membrane |
| CC | IEA | GO:0016021 | integral component of membrane |
| BP | ND | GO:0008150 | biological_process |
| BP | IEA | GO:0010469 | regulation of signaling receptor activity |
| BP | ISS | GO:0014850 | response to muscle activity |
| BP | IBA | GO:0090336 | positive regulation of brown fat cell differentiation |
| BP | ISS | GO:0090336 | positive regulation of brown fat cell differentiation |
Gene expression in normal tissue: FNDC5
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in FNDC5
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in FNDC5
CLASSFICATION
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