HEPACAM2
Summary: This gene encodes a protein related to the immunoglobulin superfamily that plays a role in mitosis. Knockdown of this gene results in prometaphase arrest, abnormal nuclear morphology and apoptosis. Poly(ADP-ribosylation) of the encoded protein promotes its translocation to centrosomes, which may stimulate centrosome maturation. A chromosomal deletion including this gene may be associated with myeloid leukemia and myelodysplastic syndrome in human patients. [provided by RefSeq, Oct 2016].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
OMIM IDMIM:614133 Ensembl IDEnsembl:ENSG00000188175 HGNC IDHGNC:HGNC:27364 PHARMGKB IDPA162390849 Map Location7q21.2 |
GO terms in HEPACAM2
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Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
CC | IEA | GO:0000139 | Golgi membrane |
CC | IBA | GO:0005794 | Golgi apparatus |
CC | IDA | GO:0005794 | Golgi apparatus |
CC | IBA | GO:0005813 | centrosome |
CC | IDA | GO:0005813 | centrosome |
CC | IBA | GO:0005819 | spindle |
Gene expression in normal tissue: HEPACAM2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in HEPACAM2
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Database | Pathway ID | Pathway Des. |
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No matching records found |
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in HEPACAM2
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
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No matching records found |