ANKRD2
Summary: This gene encodes a protein that belongs to the muscle ankyrin repeat protein (MARP) family. A similar gene in rodents is a component of a muscle stress response pathway and plays a role in the stretch-response associated with slow muscle function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
OMIM IDMIM:610734 Ensembl IDEnsembl:ENSG00000165887 HGNC IDHGNC:HGNC:495 PHARMGKB IDPA24804 Map Location10q24.2 |
Gene Categories:
TRANSCRIPTION FACTOR BINDINGGO terms in ANKRD2
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Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
MF | IEA | GO:0003682 | chromatin binding |
MF | IBA | GO:0003712 | transcription coregulator activity |
MF | NAS | GO:0008307 | structural constituent of muscle |
MF | IBA | GO:0031432 | titin binding |
MF | IPI | GO:0043422 | protein kinase B binding |
MF | IBA | GO:0061629 | RNA polymerase II sequence-specific DNA-binding transcription factor binding |
Gene expression in normal tissue: ANKRD2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ANKRD2
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Database | Pathway ID | Pathway Des. |
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No matching records found |
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
---|---|---|
iGMDRD133 | Lapatinib | 1 |
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in ANKRD2
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
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No matching records found |