PCSK1N
Summary: The protein encoded by this gene functions as an inhibitor of prohormone convertase 1, which regulates the proteolytic cleavage of neuroendocrine peptide precursors. The proprotein is further processed into multiple short peptides. A polymorphism within this gene may be associated with obesity. [provided by RefSeq, Aug 2013].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:300399 Ensembl IDEnsembl:ENSG00000102109 HGNC IDHGNC:HGNC:17301 PHARMGKB IDPA33090 Map LocationXp11.23 | |||||
GO terms in PCSK1N
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IBA | GO:0005615 | extracellular space |
| CC | IEA | GO:0005802 | trans-Golgi network |
| CC | IEA | GO:0030141 | secretory granule |
| BP | IEA | GO:0002021 | response to dietary excess |
| BP | IEA | GO:0007218 | neuropeptide signaling pathway |
| BP | IEA | GO:0009409 | response to cold |
Gene expression in normal tissue: PCSK1N
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in PCSK1N
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in PCSK1N
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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