B4GALNT3
Summary: B4GALNT3 transfers N-acetylgalactosamine (GalNAc) onto glucosyl residues to form N,N-prime-diacetyllactosediamine (LacdiNAc, or LDN), a unique terminal structure of cell surface N-glycans (Ikehara et al., 2006 [PubMed 16728562]).[supplied by OMIM, Aug 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:612220 Ensembl IDEnsembl:ENSG00000139044 HGNC IDHGNC:HGNC:24137 PHARMGKB IDPA142672564 Map Location12p13.33 | |||||
GO terms in B4GALNT3
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IDA | GO:0008376 | acetylgalactosaminyltransferase activity |
| MF | IEA | GO:0033842 | N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity |
| CC | IEA | GO:0016021 | integral component of membrane |
| CC | IEA | GO:0032580 | Golgi cisterna membrane |
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Gene expression in normal tissue: B4GALNT3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in B4GALNT3
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD134 | Sorafenib | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in B4GALNT3
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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