MRPL18


Summary: This nuclear gene encodes a protein component of the larger 39S subunit of mitochondrial ribosome. This protein may also aid in the import of nuclear-encoded 5S rRNA into mitochondria. Alternative splicing results in multiple transcript variants, most of which are not predicted to encode a protein. A pseudogene of this gene is found on chromosome 16. [provided by RefSeq, Jan 2016].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location

GO terms in MRPL18


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Term Type
Evidence Type
GO Term ID
GO Des.
MF NAS GO:0003735 structural constituent of ribosome
MF IBA GO:0008097 5S rRNA binding
MF IDA GO:0008097 5S rRNA binding
BP NAS GO:0006412 translation
BP IDA GO:0035928 rRNA import into mitochondrion
BP TAS GO:0070125 mitochondrial translational elongation
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Gene expression in normal tissue: MRPL18

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 1

Gene-drug pathway distribution

RTK signaling1

Pathways in MRPL18


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Database
Pathway ID
Pathway Des.
reactome R-HSA-392499 Metabolism of proteins
reactome R-HSA-392499 Metabolism of proteins
reactome R-HSA-5368286 Mitochondrial translation initiation
reactome R-HSA-5368287 Mitochondrial translation
reactome R-HSA-5368287 Mitochondrial translation
reactome R-HSA-5389840 Mitochondrial translation elongation
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD748 PHA-665752 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in MRPL18

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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