HPCA


Summary: The protein encoded by this gene is a member of neuron-specific calcium-binding proteins family found in the retina and brain. This protein is associated with the plasma membrane. It has similarities to proteins located in the photoreceptor cells that regulate photosignal transduction in a calcium-sensitive manner. This protein displays recoverin activity and a calcium-dependent inhibition of rhodopsin kinase. It is identical to the rat and mouse hippocalcin proteins and thought to play an important role in neurons of the central nervous system in a number of species. [provided by RefSeq, Jul 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
OMIM IDMIM:142622
PHARMGKB IDPA29417
Map Location1p35.1

GO terms in HPCA


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Term Type
Evidence Type
GO Term ID
GO Des.
BP IEA GO:0007420 brain development
BP IEA GO:0019722 calcium-mediated signaling
BP IEA GO:0031283 negative regulation of guanylate cyclase activity
BP IEA GO:0031584 activation of phospholipase D activity
BP IEA GO:0045762 positive regulation of adenylate cyclase activity
BP IEA GO:0048839 inner ear development
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Gene expression in normal tissue: HPCA

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 2

Gene-drug pathway distribution

ERK MAPK signaling1RTK signaling1

Pathways in HPCA


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD748 PHA-665752 1
iGMDRD353 PD0325901 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in HPCA

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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