HPCA
Summary: The protein encoded by this gene is a member of neuron-specific calcium-binding proteins family found in the retina and brain. This protein is associated with the plasma membrane. It has similarities to proteins located in the photoreceptor cells that regulate photosignal transduction in a calcium-sensitive manner. This protein displays recoverin activity and a calcium-dependent inhibition of rhodopsin kinase. It is identical to the rat and mouse hippocalcin proteins and thought to play an important role in neurons of the central nervous system in a number of species. [provided by RefSeq, Jul 2008].
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
Namehippocalcin OMIM IDMIM:142622 Ensembl IDEnsembl:ENSG00000121905 HGNC IDHGNC:HGNC:5144 PHARMGKB IDPA29417 Map Location1p35.1 | |||||
GO terms in HPCA
Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IEA | GO:0007420 | brain development |
| BP | IEA | GO:0019722 | calcium-mediated signaling |
| BP | IEA | GO:0031283 | negative regulation of guanylate cyclase activity |
| BP | IEA | GO:0031584 | activation of phospholipase D activity |
| BP | IEA | GO:0045762 | positive regulation of adenylate cyclase activity |
| BP | IEA | GO:0048839 | inner ear development |
Gene expression in normal tissue: HPCA
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in HPCA
Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in HPCA
Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
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