VSIG1
Summary: This gene encodes a member of the junctional adhesion molecule (JAM) family. The encoded protein contains multiple glycosylation sites at the N-terminal region, and multiple phosphorylation sites and glutamic acid/proline (EP) repeats at the C-terminal region. The gene is expressed in normal stomach and testis, as well as in gastric, esophageal and ovarian cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:300620 Ensembl IDEnsembl:ENSG00000101842 HGNC IDHGNC:HGNC:28675 PHARMGKB IDPA134944198 Map LocationXq22.3 | |||||
GO terms in VSIG1
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IEA | GO:0003382 | epithelial cell morphogenesis |
| BP | IBA | GO:0030277 | maintenance of gastrointestinal epithelium |
| BP | IEA | GO:0030277 | maintenance of gastrointestinal epithelium |
| CC | IBA | GO:0005886 | plasma membrane |
| CC | IEA | GO:0005886 | plasma membrane |
| CC | IEA | GO:0016021 | integral component of membrane |
Gene expression in normal tissue: VSIG1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in VSIG1
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD399 | Selumetinib | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in VSIG1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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