IFIT2
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| interferon induced protein with tetratricopeptide repeats 2 | MIM:147040 | Ensembl:ENSG00000119922 | HGNC:HGNC:5409 | PA29650 | 10q23.31 |
GO terms in IFIT2
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | HDA | GO:0003723 | RNA binding |
| MF | IBA | GO:0003723 | RNA binding |
| MF | IPI | GO:0005515 | protein binding |
| CC | IDA | GO:0005737 | cytoplasm |
| CC | IDA | GO:0005783 | endoplasmic reticulum |
| CC | IBA | GO:0005829 | cytosol |
| CC | TAS | GO:0005829 | cytosol |
| BP | TAS | GO:0008637 | apoptotic mitochondrial changes |
| BP | IDA | GO:0009615 | response to virus |
| BP | IMP | GO:0009615 | response to virus |
| BP | IDA | GO:0032091 | negative regulation of protein binding |
| BP | IEA | GO:0035457 | cellular response to interferon-alpha |
| BP | IDA | GO:0043065 | positive regulation of apoptotic process |
| BP | IBA | GO:0051607 | defense response to virus |
| BP | TAS | GO:0060337 | type I interferon signaling pathway |
Gene expression in normal tissue: IFIT2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in IFIT2
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1280215 | Cytokine Signaling in Immune system |
| reactome | R-HSA-168256 | Immune System |
| reactome | R-HSA-909733 | Interferon alpha/beta signaling |
| reactome | R-HSA-913531 | Interferon Signaling |
| wikipathways | WP619 | Type II interferon signaling (IFNG) |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in IFIT2
CLASSFICATION
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