ANOS1
Summary: Mutations in this gene cause the X-linked Kallmann syndrome. The encoded protein is similar in sequence to proteins known to function in neural cell adhesion and axonal migration. In addition, this cell surface protein is N-glycosylated and may have anti-protease activity. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
Nameanosmin 1 OMIM IDMIM:300836 Ensembl IDEnsembl:ENSG00000011201 HGNC IDHGNC:HGNC:6211 PHARMGKB IDPA30012 Map LocationXp22.31 | |||||
GO terms in ANOS1
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | TAS | GO:0006935 | chemotaxis |
| BP | IEA | GO:0007155 | cell adhesion |
| BP | TAS | GO:0007411 | axon guidance |
| BP | TAS | GO:0008543 | fibroblast growth factor receptor signaling pathway |
| BP | IEA | GO:0010951 | negative regulation of endopeptidase activity |
| CC | TAS | GO:0005576 | extracellular region |
Gene expression in normal tissue: ANOS1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ANOS1
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-162582 | Signal Transduction |
| reactome | R-HSA-190236 | Signaling by FGFR |
| reactome | R-HSA-190242 | FGFR1 ligand binding and activation |
| reactome | R-HSA-190373 | FGFR1c ligand binding and activation |
| reactome | R-HSA-5654726 | Negative regulation of FGFR1 signaling |
| reactome | R-HSA-5654736 | Signaling by FGFR1 |
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD284 | Palbociclib | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ANOS1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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