LGALS8


Summary: This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

Loading, please wait...
Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
OMIM IDMIM:606099
PHARMGKB IDPA30346
Map Location1q43

Gene Categories:

DRUGGABLE GENOME

GO terms in LGALS8


Loading, please wait...
Term Type
Evidence Type
GO Term ID
GO Des.
CC TAS GO:0005615 extracellular space
CC IDA GO:0005737 cytoplasm
CC IDA GO:0005829 cytosol
CC HDA GO:0016020 membrane
CC IEA GO:0031410 cytoplasmic vesicle
BP IMP GO:0098586 cellular response to virus
Showing 1 to 6 of 11 rows rows per page

Gene expression in normal tissue: LGALS8

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 1

Gene-drug pathway distribution

Cell cycle1

Pathways in LGALS8


Loading, please wait...
Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


Loading, please wait...
Drug ID
Drug Name
Model Num.
iGMDRD284 Palbociclib 1
Showing 1 to 1 of 1 rows

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in LGALS8

Loading, please wait...
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

​​​​