LGALS8
Summary: This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
Namegalectin 8 OMIM IDMIM:606099 Ensembl IDEnsembl:ENSG00000116977 HGNC IDHGNC:HGNC:6569 PHARMGKB IDPA30346 Map Location1q43 |
Gene Categories:
DRUGGABLE GENOMEGO terms in LGALS8
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Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
CC | TAS | GO:0005615 | extracellular space |
CC | IDA | GO:0005737 | cytoplasm |
CC | IDA | GO:0005829 | cytosol |
CC | HDA | GO:0016020 | membrane |
CC | IEA | GO:0031410 | cytoplasmic vesicle |
BP | IMP | GO:0098586 | cellular response to virus |
Gene expression in normal tissue: LGALS8
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in LGALS8
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Database | Pathway ID | Pathway Des. |
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No matching records found |
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
---|---|---|
iGMDRD284 | Palbociclib | 1 |
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in LGALS8
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
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No matching records found |