NTSR1
Summary: Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:162651 Ensembl IDEnsembl:ENSG00000101188 HGNC IDHGNC:HGNC:8039 PHARMGKB IDPA31821 Map Location20q13.33 | |||||
GO terms in NTSR1
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | TAS | GO:0004930 | G-protein coupled receptor activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IDA | GO:0016492 | G-protein coupled neurotensin receptor activity |
| MF | IMP | GO:0016492 | G-protein coupled neurotensin receptor activity |
| MF | IPI | GO:0042802 | identical protein binding |
| MF | IEA | GO:0042803 | protein homodimerization activity |
Gene expression in normal tissue: NTSR1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in NTSR1
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa04020 | Calcium signaling pathway - Homo sapiens (human) |
| kegg | hsa04080 | Neuroactive ligand-receptor interaction - Homo sapiens (human) |
| wikipathways | WP117 | GPCRs, Other |
| wikipathways | WP24 | Peptide GPCRs |
| wikipathways | WP455 | GPCRs, Class A Rhodopsin-like |
| reactome | R-HSA-162582 | Signal Transduction |
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in NTSR1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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