DERA
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| deoxyribose-phosphate aldolase | Ensembl:ENSG00000023697 | HGNC:HGNC:24269 | PA134943367 | 12p12.3 |
GO terms in DERA
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | TAS | GO:0006098 | pentose-phosphate shunt |
| BP | IBA | GO:0009264 | deoxyribonucleotide catabolic process |
| BP | IBA | GO:0016052 | carbohydrate catabolic process |
| BP | TAS | GO:0043312 | neutrophil degranulation |
| BP | IDA | GO:0046121 | deoxyribonucleoside catabolic process |
| BP | IEA | GO:0046386 | deoxyribose phosphate catabolic process |
| CC | TAS | GO:0005576 | extracellular region |
| CC | IDA | GO:0005634 | nucleus |
| CC | TAS | GO:0005829 | cytosol |
| CC | TAS | GO:0034774 | secretory granule lumen |
| CC | TAS | GO:1904813 | ficolin-1-rich granule lumen |
| MF | IBA | GO:0004139 | deoxyribose-phosphate aldolase activity |
| MF | IDA | GO:0004139 | deoxyribose-phosphate aldolase activity |
| MF | TAS | GO:0004139 | deoxyribose-phosphate aldolase activity |
Gene expression in normal tissue: DERA
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in DERA
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| smpdb | SMP00031 | Pentose Phosphate Pathway |
| smpdb | SMP00518 | Glucose-6-phosphate dehydrogenase deficiency |
| smpdb | SMP00519 | Ribose-5-phosphate isomerase deficiency |
| smpdb | SMP00520 | Transaldolase deficiency |
| kegg | hsa00030 | Pentose phosphate pathway - Homo sapiens (human) |
| humancyc | PWY-7180 | 2,-deoxy-α-D-ribose 1-phosphate degradation |
| reactome | R-HSA-1430728 | Metabolism |
| reactome | R-HSA-168249 | Innate Immune System |
| reactome | R-HSA-168256 | Immune System |
| reactome | R-HSA-6798695 | Neutrophil degranulation |
| reactome | R-HSA-71336 | Pentose phosphate pathway |
| reactome | R-HSA-71387 | Metabolism of carbohydrates |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in DERA
CLASSFICATION
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