RSF1
Summary: This gene encodes a nuclear protein that interacts with hepatitis B virus X protein (HBX) and facilitates transcription of hepatitis B virus genes by the HBX transcription activator, suggesting a role for this interaction in the virus life cycle. This protein also interacts with SNF2H protein to form the RSF chromatin-remodeling complex, where the SNF2H subunit functions as the nucleosome-dependent ATPase, and this protein as the histone chaperone. [provided by RefSeq, Sep 2011].
Loading, please wait...
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
OMIM IDMIM:608522 Ensembl IDEnsembl:ENSG00000048649 HGNC IDHGNC:HGNC:18118 PHARMGKB IDPA29210 Map Location11q14.1 |
GO terms in RSF1
Loading, please wait...
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
BP | IDA | GO:0006334 | nucleosome assembly |
BP | IDA | GO:0006338 | chromatin remodeling |
BP | IDA | GO:0006352 | DNA-templated transcription, initiation |
BP | IDA | GO:0016584 | nucleosome positioning |
BP | TAS | GO:0034080 | CENP-A containing nucleosome assembly |
BP | IDA | GO:0043392 | negative regulation of DNA binding |
Gene expression in normal tissue: RSF1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in RSF1
Loading, please wait...
Database | Pathway ID | Pathway Des. |
---|---|---|
reactome | R-HSA-1640170 | Cell Cycle |
reactome | R-HSA-606279 | Deposition of new CENPA-containing nucleosomes at the centromere |
reactome | R-HSA-73886 | Chromosome Maintenance |
reactome | R-HSA-774815 | Nucleosome assembly |
Showing 1 to 4 of 4 rows
Gene-Drug: Aster Plot
Loading, please wait...
Drug ID | Drug Name | Model Num. |
---|---|---|
iGMDRD221 | Tamoxifen | 1 |
Showing 1 to 1 of 1 rows
Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in RSF1
Loading, please wait...
Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
---|---|---|---|---|---|---|---|---|
No matching records found |