SLC6A20


Summary: Transport of small hydrophilic substances across cell membranes is mediated by substrate-specific transporter proteins which have been classified into several families of related genes. The protein encoded by this gene is a member of the subgroup of transporter with unidentified substrates within the Na+ and Cl- coupled transporter family. This gene is expressed in kidney, and its alternative splicing generates 2 transcript variants. [provided by RefSeq, Jul 2008].

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PHARMGKB ID
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GO terms in SLC6A20


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IBA GO:0005215 transporter activity
MF IEA GO:0005328 neurotransmitter:sodium symporter activity
MF IPI GO:0005515 protein binding
MF IDA GO:0015171 amino acid transmembrane transporter activity
MF TAS GO:0015171 amino acid transmembrane transporter activity
MF IBA GO:0015193 L-proline transmembrane transporter activity
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Gene expression in normal tissue: SLC6A20

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 3

Gene-drug pathway distribution

ERK MAPK signaling1RTK signaling1

Pathways in SLC6A20


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Database
Pathway ID
Pathway Des.
reactome R-HSA-1643685 Disease
reactome R-HSA-352230 Amino acid transport across the plasma membrane
reactome R-HSA-382551 Transport of small molecules
reactome R-HSA-425366 Transport of bile salts and organic acids, metal ions and amine compounds
reactome R-HSA-425393 Transport of inorganic cations/anions and amino acids/oligopeptides
reactome R-HSA-425407 SLC-mediated transmembrane transport
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD491 TAE-684 1
iGMDRD353 PD0325901 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in SLC6A20

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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