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SEPT11

Summary: SEPT11 belongs to the conserved septin family of filament-forming cytoskeletal GTPases that are involved in a variety of cellular functions including cytokinesis and vesicle trafficking (Hanai et al., 2004 [PubMed 15196925]; Nagata et al., 2004 [PubMed 15485874]).[supplied by OMIM, Jul 2009].

Name	OMIM ID	Ensembl ID	HGNC ID	PHARMGKB ID	Map Location
septin 11	MIM:612887	Ensembl:ENSG00000138758	HGNC:HGNC:25589	PA128394688	4q21.1

GO terms in SEPT11

Term Type	Evidence Type	GO Term ID	GO Des.
CC	IDA	GO:0001725	stress fiber
CC	IEA	GO:0005737	cytoplasm
CC	IBA	GO:0005940	septin ring
CC	IBA	GO:0015630	microtubule cytoskeleton
CC	IEA	GO:0030054	cell junction
CC	IEA	GO:0030424	axon
CC	IBA	GO:0031105	septin complex
CC	IBA	GO:0032153	cell division site
CC	IBA	GO:0032160	septin filament array
CC	IEA	GO:0043197	dendritic spine
BP	IBA	GO:0000281	mitotic cytokinesis
BP	IBA	GO:0000921	septin ring assembly
BP	IEA	GO:0007049	cell cycle
BP	IBA	GO:0034613	cellular protein localization
BP	IDA	GO:0051291	protein heterooligomerization
BP	IEA	GO:0051301	cell division
BP	IBA	GO:0060271	cilium assembly
MF	IBA	GO:0003924	GTPase activity
MF	IPI	GO:0005515	protein binding
MF	IEA	GO:0005525	GTP binding
MF	IBA	GO:0032947	protein-containing complex scaffold activity

Gene expression in normal tissue: SEPT11

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Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in SEPT11

Database	Pathway ID	Pathway Des.
kegg	hsa05100	Bacterial invasion of epithelial cells - Homo sapiens (human)

Gene-Drug: Aster Plot

Drug ID	Drug Name	Model Num.
iGMDRD491	TAE-684	1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in SEPT11

SITE

DATATYPES

CLASSFICATION

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