SEPT3
Summary: This gene belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression is upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, May 2018].
Loading, please wait...
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
Nameseptin 3 OMIM IDMIM:608314 Ensembl IDEnsembl:ENSG00000100167 HGNC IDHGNC:HGNC:10750 PHARMGKB IDPA24355 Map Location22q13.2 | |||||
GO terms in SEPT3
Loading, please wait...
Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IEA | GO:0005737 | cytoplasm |
| CC | IEA | GO:0005856 | cytoskeleton |
| CC | IBA | GO:0005940 | septin ring |
| CC | IBA | GO:0015630 | microtubule cytoskeleton |
| CC | IEA | GO:0030054 | cell junction |
| CC | IBA | GO:0031105 | septin complex |
Gene expression in normal tissue: SEPT3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SEPT3
Loading, please wait...
Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa05100 | Bacterial invasion of epithelial cells - Homo sapiens (human) |
Showing 1 to 1 of 1 rows
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SEPT3
Loading, please wait...
Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
Copyright © 2018 Modellab | All Rights Reserved
Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.