DPYSL5
Summary: This gene encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development. Antibodies to the encoded protein were found in some patients with neurologic symptoms who had paraneoplastic syndrome. A pseudogene of this gene is found on chromosome 11. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:608383 Ensembl IDEnsembl:ENSG00000157851 HGNC IDHGNC:HGNC:20637 PHARMGKB IDPA134927413 Map Location2p23.3 | |||||
GO terms in DPYSL5
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | TAS | GO:0007165 | signal transduction |
| BP | TAS | GO:0007399 | nervous system development |
| BP | IEA | GO:0007411 | axon guidance |
| CC | TAS | GO:0005829 | cytosol |
| CC | IEA | GO:0030425 | dendrite |
| CC | IEA | GO:0043025 | neuronal cell body |
Gene expression in normal tissue: DPYSL5
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in DPYSL5
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1266738 | Developmental Biology |
| reactome | R-HSA-373755 | Semaphorin interactions |
| reactome | R-HSA-399956 | CRMPs in Sema3A signaling |
| reactome | R-HSA-422475 | Axon guidance |
| kegg | hsa04360 | Axon guidance - Homo sapiens (human) |
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Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in DPYSL5
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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