SLC44A2
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| solute carrier family 44 member 2 | MIM:606106 | Ensembl:ENSG00000129353 | HGNC:HGNC:17292 | PA142670899 | 19p13.2 |
Gene Categories:
TRANSPORTERGO terms in SLC44A2
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | TAS | GO:0015220 | choline transmembrane transporter activity |
| BP | TAS | GO:0006656 | phosphatidylcholine biosynthetic process |
| BP | TAS | GO:0015871 | choline transport |
| BP | HMP | GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling |
| BP | TAS | GO:0043312 | neutrophil degranulation |
| BP | TAS | GO:0055085 | transmembrane transport |
| CC | HDA | GO:0005765 | lysosomal membrane |
| CC | TAS | GO:0005886 | plasma membrane |
| CC | TAS | GO:0016021 | integral component of membrane |
| CC | TAS | GO:0035579 | specific granule membrane |
| CC | HDA | GO:0070062 | extracellular exosome |
Gene expression in normal tissue: SLC44A2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SLC44A2
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa05231 | Choline metabolism in cancer - Homo sapiens (human) |
| smpdb | SMP02313 | sarcosine oncometabolite pathway |
| reactome | R-HSA-1430728 | Metabolism |
| reactome | R-HSA-1483191 | Synthesis of PC |
| reactome | R-HSA-1483206 | Glycerophospholipid biosynthesis |
| reactome | R-HSA-1483257 | Phospholipid metabolism |
| reactome | R-HSA-168249 | Innate Immune System |
| reactome | R-HSA-168256 | Immune System |
| reactome | R-HSA-382551 | Transport of small molecules |
| reactome | R-HSA-425366 | Transport of bile salts and organic acids, metal ions and amine compounds |
| reactome | R-HSA-425407 | SLC-mediated transmembrane transport |
| reactome | R-HSA-556833 | Metabolism of lipids |
| reactome | R-HSA-6798695 | Neutrophil degranulation |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SLC44A2
CLASSFICATION
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