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TINAGL1

Summary: The protein encoded by this gene is similar in sequence to tubulointerstitial nephritis antigen, a secreted glycoprotein that is recognized by antibodies in some types of immune-related tubulointerstitial nephritis. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011].

Name	OMIM ID	Ensembl ID	HGNC ID	PHARMGKB ID	Map Location
tubulointerstitial nephritis antigen like 1	MIM:616064	Ensembl:ENSG00000142910	HGNC:HGNC:19168	PA38810	1p35.2

Gene Categories:

DRUGGABLE GENOME PROTEASE

GO terms in TINAGL1

Term Type	Evidence Type	GO Term ID	GO Des.
CC	NAS	GO:0005576	extracellular region
CC	IBA	GO:0005615	extracellular space
CC	ISS	GO:0005615	extracellular space
CC	IBA	GO:0005764	lysosome
CC	HDA	GO:0062023	collagen-containing extracellular matrix
CC	HDA	GO:0062023	collagen-containing extracellular matrix
CC	HDA	GO:0070062	extracellular exosome
BP	IEA	GO:0006898	receptor-mediated endocytosis
BP	IEA	GO:0006955	immune response
BP	IBA	GO:0007155	cell adhesion
BP	TAS	GO:0016197	endosomal transport
BP	IBA	GO:0051603	proteolysis involved in cellular protein catabolic process
MF	IBA	GO:0004197	cysteine-type endopeptidase activity
MF	IEA	GO:0005044	scavenger receptor activity
MF	NAS	GO:0005201	extracellular matrix structural constituent
MF	IPI	GO:0005515	protein binding
MF	IEA	GO:0030247	polysaccharide binding
MF	IEA	GO:0043236	laminin binding

Gene expression in normal tissue: TINAGL1

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Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in TINAGL1

Database	Pathway ID	Pathway Des.

Gene-Drug: Aster Plot

Drug ID	Drug Name	Model Num.
iGMDRD134	Sorafenib	2

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TINAGL1

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DATATYPES

CLASSFICATION

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